Jiake Xu Selected Research

Triterpenes

1/2022	Roburic acid attenuates osteoclastogenesis and bone resorption by targeting RANKL-induced intracellular signaling pathways.
1/2019	Asiaticoside, a component of Centella asiatica attenuates RANKL-induced osteoclastogenesis via NFATc1 and NF-κB signaling pathways.

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Jiake Xu Research Topics

Disease

83	Bone Resorption 03/2024 - 04/2003
57	Neoplasms (Cancer) 10/2023 - 08/2003
49	Osteoporosis 02/2024 - 09/2011
29	Osteolysis 02/2024 - 11/2004
17	Bone Diseases (Bone Disease) 01/2022 - 11/2004
16	Inflammation (Inflammations) 02/2024 - 02/2009
12	Osteosarcoma (Osteogenic Sarcoma) 01/2023 - 01/2018
7	Osteoarthritis 09/2023 - 06/2013
7	Neoplasm Metastasis (Metastasis) 04/2023 - 08/2003
7	Rheumatoid Arthritis 10/2021 - 04/2015
7	Arthritis (Polyarthritis) 02/2020 - 02/2009
6	Spinal Cord Injuries (Spinal Cord Injury) 03/2022 - 01/2019
6	Breast Neoplasms (Breast Cancer) 03/2021 - 01/2016
6	Osteitis Deformans (Paget's Disease of Bone) 01/2021 - 07/2006
5	Osteonecrosis (Kienbock's Disease) 03/2024 - 06/2013
5	Metabolic Bone Diseases (Osteopenia) 06/2023 - 01/2017
5	Postmenopausal Osteoporosis 07/2022 - 11/2015
4	Giant Cell Tumor of Bone 01/2022 - 08/2003
3	Wounds and Injuries (Trauma) 02/2024 - 01/2014
3	Periodontal Diseases (Periodontal Disease) 08/2023 - 12/2021
3	Infections 01/2019 - 05/2016
3	Experimental Arthritis 11/2018 - 05/2013
2	Disease Progression 03/2024 - 02/2020
2	Joint Diseases (Joint Disease) 03/2024 - 06/2013
2	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2023 - 12/2022
2	Obesity 09/2023 - 01/2022
2	Prosthesis Failure 08/2023 - 01/2019
2	Metabolic Diseases (Metabolic Disease) 04/2023 - 01/2017
2	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 01/2022
2	Periodontitis 12/2021 - 02/2009
2	Cerebral Hemorrhage 01/2021 - 01/2020
2	Osteopetrosis 01/2021 - 01/2016
2	Hypoxia (Hypoxemia) 01/2021 - 01/2020
2	Pain (Aches) 01/2019 - 01/2016
2	Carcinogenesis 11/2018 - 03/2018
2	Bone Fractures (Bone Fracture) 03/2018 - 01/2016

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 03/2024 - 06/2004
14	LigandsIBA 01/2023 - 08/2003
13	Therapeutic UsesIBA 11/2023 - 02/2009
11	Estrogens (Estrogen)FDA Link 11/2023 - 11/2015
10	Tartrate-Resistant Acid PhosphataseIBA 02/2024 - 11/2016
10	RNA (Ribonucleic Acid)IBA 01/2023 - 10/2020
8	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 12/2018
8	AntioxidantsIBA 09/2023 - 01/2016
8	CalciumIBA 05/2022 - 09/2007
8	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2013
7	FlavonoidsIBA 04/2023 - 09/2011
7	TitaniumIBA 01/2022 - 01/2015
7	LipopolysaccharidesIBA 01/2019 - 11/2004
6	Transcription Factors (Transcription Factor)IBA 01/2022 - 01/2018
5	CytokinesIBA 02/2024 - 05/2015
5	parthenolideIBA 01/2023 - 11/2004
5	Durapatite (Hydroxylapatite)IBA 01/2022 - 06/2015
5	NF-kappa B (NF-kB)IBA 12/2009 - 11/2004
4	HydrogelsIBA 02/2024 - 01/2017
4	Small Interfering RNA (siRNA)IBA 09/2023 - 01/2016
4	SesquiterpenesIBA 01/2023 - 11/2004
4	Messenger RNA (mRNA)IBA 07/2022 - 08/2003
4	RANK LigandIBA 01/2021 - 08/2006
4	Cathepsin KIBA 01/2020 - 09/2007
4	Mitogen-Activated Protein KinasesIBA 01/2020 - 07/2014
4	MicroRNAs (MicroRNA)IBA 12/2019 - 06/2015
4	Adenosine Triphosphatases (ATPase)IBA 12/2019 - 04/2003
3	GlucocorticoidsIBA 03/2024 - 05/2013
3	IntegrinsIBA 04/2023 - 01/2019
3	Small Cytoplasmic RNAIBA 01/2023 - 01/2023
3	LactonesIBA 01/2023 - 11/2004
3	LuciferasesIBA 05/2022 - 01/2015
3	Actins (F Actin)IBA 01/2022 - 01/2019
3	UbiquitinIBA 01/2021 - 08/2006
3	Polysaccharides (Glycans)IBA 12/2018 - 01/2018
3	Docetaxel (Taxotere)FDA Link 02/2017 - 09/2015
3	CollagenIBA 01/2017 - 01/2014
3	Protein Kinase CIBA 06/2015 - 12/2003
2	tilirosideIBA 02/2024 - 09/2019
2	fibroblast growth factor 21IBA 02/2024 - 01/2020
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2024 - 04/2013
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 11/2023 - 01/2020
2	Caspase 3 (Caspase-3)IBA 09/2023 - 06/2012
2	TNF Receptor-Associated Factor 6 (TRAF6)IBA 06/2023 - 05/2016
2	SteroidsIBA 01/2023 - 01/2020
2	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 01/2023 - 06/2004
2	TriterpenesIBA 01/2022 - 01/2019
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 01/2016
2	Protein Kinases (Protein Kinase)IBA 01/2021 - 01/2020
2	Lysine (L-Lysine)FDA Link 01/2021 - 01/2016
2	Sorting NexinsIBA 01/2021 - 01/2016
2	Long Noncoding RNAIBA 11/2020 - 01/2020
2	Opioid Analgesics (Opioids)IBA 01/2019 - 01/2016
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2019 - 01/2016
2	Bone Density Conservation AgentsIBA 01/2019 - 01/2017
2	polyglycerolIBA 10/2018 - 01/2016
2	Folic Acid (Vitamin M)FDA LinkGeneric 10/2018 - 01/2016
2	Nerve Growth Factors (Neurotrophins)IBA 03/2018 - 01/2016

Therapy/Procedure

38	Therapeutics 02/2024 - 08/2009
15	Ovariectomy (Oophorectomy) 02/2024 - 11/2015
6	Drug Therapy (Chemotherapy) 01/2023 - 07/2012
4	Arthroplasty 08/2023 - 01/2019
3	Complementary Therapies (Alternative Medicine) 01/2017 - 09/2011
2	Injections 12/2021 - 01/2020